Benzene, 1-isocyanato-2-methyl-3-nitro-

Benzene, 1-isocyanato-2-methyl-3-nitro- - Names and Identifiers

Name	2-methyl-3-nitrophenyl isocyanate
Synonyms	ZINC02384725 478350_ALDRICH 2-METHYL-3-NITROPHENYL ISOCYANATE 2-methyl-3-nitrophenyl isocyanate 1-isocyanato-2-methyl-3-nitrobenzene Benzene, 1-isocyanato-2-methyl-3-nitro-
CAS	23695-15-0
InChI	InChI=1/C8H6N2O3/c1-6-7(9-5-11)3-2-4-8(6)10(12)13/h2-4H,1H3

Benzene, 1-isocyanato-2-methyl-3-nitro- - Physico-chemical Properties

Molecular Formula	C8H6N2O3
Molar Mass	178.14
Density	1.4114 (rough estimate)
Melting Point	34-37°C
Boling Point	118°C 2,8mm
Flash Point	>110°C
Vapor Presure	0.00425mmHg at 25°C
BRN	9120119
Storage Condition	Room Temprature
Sensitive	Moisture Sensitive
Refractive Index	1.6000 (estimate)
MDL	MFCD00037046

Benzene, 1-isocyanato-2-methyl-3-nitro- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R42 - May cause sensitization by inhalation
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing.
UN IDs	2206
Hazard Class	6.1
Packing Group	III

Benzene, 1-isocyanato-2-methyl-3-nitro- - Introduction

2-methyl-3-nitrophenyl isocyyanate is an organic compound with the chemical formula C8H6N2O3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: yellow or light yellow crystalline solid.
2. Melting Point: about 73-75 ° C.
3. Boiling Point: will decompose under normal pressure.

Use:
1. 2-methyl-3-nitrophenyl isocyanate can be used as an intermediate in organic synthesis.
2. It has certain applications in drug synthesis, mainly for the synthesis of some compounds containing amino units.
3. Can also be used as dyes and pigments intermediates.

Method:
2-methyl-3-nitrophenyl isocyanate can be obtained by P-nitrating methylbenzene. The specific preparation process is as follows:
1. First, dissolve methylbenzene in concentrated nitric acid, and then add sulfuric acid as a catalyst.
2. Heating the reaction system to an appropriate temperature for the nitration reaction.
3. After the end of the reaction, the product was isolated and purified by cooling and crystallization.

Safety Information:
1. 2-methyl-3-nitrophenyl isocyanate is a harmful chemical that may cause irritation to the human body.
2. During use, attention should be paid to avoid contact with skin, mouth and eyes, and take good ventilation measures.
3. Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during operation.
4. When cleaning, attention should be paid to prevent the diffusion of compounds in the environment.
5. Please read and follow the MSDS (safety data sheet) of the chemical and the relevant safety procedures during operation.

Last Update：2024-04-09 21:01:54